This is not the case for metoprolol ER (generic for Toprol-XL), however.Įach Metoprolol ER tablet contains a large number of tiny controlled release pellets, which are evenly dispersed throughout the tablet. Metoprolol ER Release Mechanismįor most extended-release medications, altering the tablet/capsule will destroy the extended-release mechanism, causing the entire dose to be delivered at once, which can increase the risk of overdose and side effects. In fact, the tablets have a 'score' line, and the drug is one of the few extended-release medications that are able to be cut safely due to how the extended-release mechanism of metoprolol succinate works. Thanks for contacting us! Yes, Toprol XL (metoprolol succinate extended-release) can be cut or split in half.